Top benefits of african mango diet pills

May 7, 2012Download as PPTX, PDF1 like4,542 views

http://www.mangodiet.com where weight loss product called African Mango Diet Pills were found. The African mango diet plan is considered as the latest breakthrough in the world of weight loss. For those who never give up on their dreams regardless of the numerous failures they have committed, this kind of product still brings the same excitement and hope just like with the other stuffs they have tried before. This kind of attitude is very important to be instilled in one person if he really wants to move closer to his goal.

Top benefits of african mango diet pills

Are you one of the many people who are frustrated with the
diet plan you are following since it is not giving you any
reason to smile and to be happy. Are you also considering
of abandoning your goal of reaching your desired weight
before you join your friends in the sports competition few
weeks from now? If you are one of these individuals, it is
really understandable if ever you contemplating of quitting
on your weight loss program. However, with the help of the
information that this article will give you, reconsidering of
your decision is feasible once you get to know the weight
loss product called African Mango diet pills. Know the
weight loss product called African Mango diet pills which
can be found at www.mangodiet.com

In case you are not familiar with the mentioned weight loss product above,
there is nothing for you to be worried of since everything that you want to
know about it can be accessed in the different African Mango reviews.
These reviews are free and can be accessed in numerous sites in the
Internet which would definitely provide you the information that you are
looking for. The feedbacks that you will be able to gather from the different
reviews will surely come in handy in helping you to arrive at your final
decision.

However, it will also not be
surprising if you will
encounter some negative
things or rumors about the
mentioned product above.
One of these is the one that
pertains to the African
Mango scam which is for
sure can make you stop
right on your track. The
thought of spending your
money, hope that you have
the best buy and the
solution but only to fail and
be disappointed with the
result you would get is
something that most people
would not like to happen.
For sure, you will also do
everything just to be sure
that you will not also suffer
from this situation.

Another thing that you must be wary of is the African Mango side effects. This is
another reason why there are some people who are having second thoughts or
hesitating of purchasing this product. These people cannot be blamed to have
this kind of mentality as most of them have experienced numerous failed
attempts in the task of shedding of their excess weights. Despite that the market
offers the huge selection of the weight loss products, it just cannot be denied
that there is always the possibility that you might buy the wrong product that will
only disappoint and put your money in waste.

•This supplement can suppress your appetite and would make you feel less
hungry all throughout the day. Contrary to what others are thinking, this pill will
not place your health and stamina at risk as it will still allow you to work and do
your regular tasks with relative ease.

•This product does not have any side effects since it is made of natural
ingredients unless you have some allergic on its ingredients.
•The African Mango diet pills contain the essential vitamins and the nutrients
that will enhance your stamina and allow you to remain strong despite the
weight that you will shed with the help of this product.

What you have read are the great things that you can expect for the mentioned
weight loss product to provide to you. So if you really want to achieve significant
changes in your body, then you should grab the opportunity to have the benefits
of the amazing African Mango diet pills.

The future of SEO is trending toward a more human-first and user-centric approach, powered by AI intelligence and collaboration. Are you ready? Watch as we explore which SEO trends to prioritize to achieve sustainable growth and deliver reliable results. We’ll dive into best practices to adapt your strategy around industry-wide disruptions like SGE, how to navigate the top challenges SEO professionals are facing, and proven tactics for prioritizing quality and building trust. You’ll hear: - The top SEO trends to prioritize in 2024 to achieve long-term success. - Predictions for SGE’s impact, and how to adapt. - What E-E-A-T really means, and how to implement it holistically (hint: it’s never been more important). With Zack Kadish and Alex Carchietta, we’ll show you which SEO trends to ignore and which to focus on, along with the solution to overcoming rapid, significant and disruptive Google algorithm updates. If you’re looking to cut through the noise of constant SEO and content trends to drive success, you won’t want to miss this webinar.

Storytelling For The Web: Integrate Storytelling in your Design ProcessChiara Aliotta

Artificial Intelligence, Data and Competition – SCHREPEL – June 2024 OECD dis...OECD Directorate for Financial and Enterprise Affairs

This presentation by Thibault Schrepel, Associate Professor of Law at Vrije Universiteit Amsterdam University, was made during the discussion “Artificial Intelligence, Data and Competition” held at the 143rd meeting of the OECD Competition Committee on 12 June 2024. More papers and presentations on the topic can be found at oe.cd/aicomp. This presentation was uploaded with the author’s consent.

How to Leverage AI to Boost Employee Wellness - Lydia Di Francesco - SocialHR...SocialHRCamp

Speaker: Lydia Di Francesco In this workshop, participants will delve into the realm of AI and its profound potential to revolutionize employee wellness initiatives. From stress management to fostering work-life harmony, AI offers a myriad of innovative tools and strategies that can significantly enhance the wellbeing of employees in any organization. Attendees will learn how to effectively leverage AI technologies to cultivate a healthier, happier, and more productive workforce. Whether it's utilizing AI-powered chatbots for mental health support, implementing data analytics to identify internal, systemic risk factors, or deploying personalized wellness apps, this workshop will equip participants with actionable insights and best practices to harness the power of AI for boosting employee wellness. Join us and discover how AI can be a strategic partner towards a culture of wellbeing and resilience in the workplace.

2024 State of Marketing Report – by HubspotMarius Sescu

https://www.hubspot.com/state-of-marketing · Scaling relationships and proving ROI · Social media is the place for search, sales, and service · Authentic influencer partnerships fuel brand growth · The strongest connections happen via call, click, chat, and camera. · Time saved with AI leads to more creative work · Seeking: A single source of truth · TLDR; Get on social, try AI, and align your systems. · More human marketing, powered by robots

Everything You Need To Know About ChatGPTExpeed Software

ChatGPT is a revolutionary addition to the world since its introduction in 2022. A big shift in the sector of information gathering and processing happened because of this chatbot. What is the story of ChatGPT? How is the bot responding to prompts and generating contents? Swipe through these slides prepared by Expeed Software, a web development company regarding the development and technical intricacies of ChatGPT!

Product Design Trends in 2024 | Teenage EngineeringsPixeldarts

How Race, Age and Gender Shape Attitudes Towards Mental HealthThinkNow

Mental health has been in the news quite a bit lately. Dozens of U.S. states are currently suing Meta for contributing to the youth mental health crisis by inserting addictive features into their products, while the U.S. Surgeon General is touring the nation to bring awareness to the growing epidemic of loneliness and isolation. The country has endured periods of low national morale, such as in the 1970s when high inflation and the energy crisis worsened public sentiment following the Vietnam War. The current mood, however, feels different. Gallup recently reported that national mental health is at an all-time low, with few bright spots to lift spirits. To better understand how Americans are feeling and their attitudes towards mental health in general, ThinkNow conducted a nationally representative quantitative survey of 1,500 respondents and found some interesting differences among ethnic, age and gender groups. Technology For example, 52% agree that technology and social media have a negative impact on mental health, but when broken out by race, 61% of Whites felt technology had a negative effect, and only 48% of Hispanics thought it did. While technology has helped us keep in touch with friends and family in faraway places, it appears to have degraded our ability to connect in person. Staying connected online is a double-edged sword since the same news feed that brings us pictures of the grandkids and fluffy kittens also feeds us news about the wars in Israel and Ukraine, the dysfunction in Washington, the latest mass shooting and the climate crisis. Hispanics may have a built-in defense against the isolation technology breeds, owing to their large, multigenerational households, strong social support systems, and tendency to use social media to stay connected with relatives abroad. Age and Gender When asked how individuals rate their mental health, men rate it higher than women by 11 percentage points, and Baby Boomers rank it highest at 83%, saying it’s good or excellent vs. 57% of Gen Z saying the same. Gen Z spends the most amount of time on social media, so the notion that social media negatively affects mental health appears to be correlated. Unfortunately, Gen Z is also the generation that’s least comfortable discussing mental health concerns with healthcare professionals. Only 40% of them state they’re comfortable discussing their issues with a professional compared to 60% of Millennials and 65% of Boomers. Race Affects Attitudes As seen in previous research conducted by ThinkNow, Asian Americans lag other groups when it comes to awareness of mental health issues. Twenty-four percent of Asian Americans believe that having a mental health issue is a sign of weakness compared to the 16% average for all groups. Asians are also considerably less likely to be aware of mental health services in their communities (42% vs. 55%) and most likely to seek out information on social media (51% vs. 35%).

PRETERM LABOR.pptx FOR NURSING STUDENTS CREATED BY KIRAN KARETHAKIRAN KARETHA

PREMATURE LABOUR/ PRETERM LABOUR DEFINITION:  Pre term labour is defined by WHO as onset of labour prior to the completion of 37 weeks of gestation in a pregnancy beyond 20 weeks of gestation. INCIDENCE:  Globally, approximately 1 in 10 babies are born preterm (before 37 completed weeks of gestation), with an estimated 13.4 million preterm births annually. This means the incidence of preterm birth is roughly 10-11% worldwide.  In India, about 12% of babies are born preterm, which is higher than neighboring countries. ETIOLOGY:  In about 50%, the cause of preterm labour is not known- IDIOPATHIC  Some of the high-risk factors are:  HISTORY: previous history of abortion or preterm delivery Recurrent UTI Smoking habits Low socio-economic & nutritional status Previous abortion history Malpresentation  COMPLICATIONS IN PRESENT PREGNANCY: it may be due to maternal, fetal and placental. SIGN AND SYMPTOMS:  Backache  Contractions every 10 minutes, are more often  Cramping in lower abdomen  Menstrual like cramps  Fluid leaking from vagina  Flu like symptoms  Increased pressure in pelvis  Increased vaginal bleeding  Regular uterine activity  Vaginal spotting DIAGNOSIS:  Regular uterine contractions with or without pain (at least one in every 10 minutes.)  Dilation (2 cm or more) & effacement (80%) of the cervix  Length of cervix (2.5 cm or more.)  Funneling of internal OS INVESTIGATIONS:  Blood test  Urine analysis, urine culture and sensitivity  Cervicovaginal swab: culture and fibronectin test  Serum electrolyte and glucose level  USG COMPLICATION:  Birth of a pre-term baby A pre-term baby usually has following problems: • Low birth weight • Birth asphyxia • Neonatal jaundice • Underdeveloped organs etc. PREVENTIVE MEASURES: However, it is not possible to prevent occurrence of preterm labour completely, though its prevalence can be reduced using various measures at following three levels- 1) Prevention at primary level 2) Prevention at secondary level 3) Prevention at tertiary level 1) Prevention at primary level  In this, actions are taken prior to the onset of any disease which reduce or remove the possibility for occurring a disease.  For preventing preterm labour, following measures are applied at primary level. • Encourage the pregnant, to visit antenatal clinic regularly. • To identify high risk factors at its incipient stage and to provide appropriate treatment accordingly. • To provide special care to the women who have history of previous spontaneous abortion or preterm labour. • Advice the pregnant women regarding: Not to smoke and use of alcohol To take well balanced diet Avoid hard work Iron folic acid supplementation Maintaining adequate personal and environmental hygiene To contact the doctor immediately if any abnormal symptoms arise 2) Prevention at secondary level  In this level, actions are taken at the incipient stage of the disease so that it can be diagnosed.

Title: 📊 Pharmacoeconomics: History, Principles, Methods, and Applicationssakshiaggarwal979034

📌 Description: Pharmacoeconomics is a vital field that examines the economic impact of pharmaceutical products and healthcare services. This presentation provides a detailed overview of pharmacoeconomic principles, methodologies, and their significance in healthcare decision-making. It covers essential topics such as cost analysis, evaluation perspectives, and humanistic assessment methods. 💡 Key Topics Covered: ✔ History and Evolution of Pharmacoeconomics ✔ Goals and Objectives of Pharmacoeconomic Studies ✔ Cost Analysis & Consequences (Outcomes) ✔ Different Pharmacoeconomic Methodologies (Cost-Minimization, Cost-Effectiveness, Cost-Utility, Cost-Benefit) ✔ Perspectives in Economic Evaluations (Payer, Patient, Society) ✔ Role of Pharmacoeconomics in Drug Safety & Pharmacovigilance ✔ Humanistic Evaluation Methods (Quality of Life & Patient-Reported Outcomes) ✔ Importance of Pharmacoeconomics in Policy & Healthcare Decisions

Nervous System (Neurons and Neuroglia).pptxPranaliChandurkar2

Nervous tissue comprises two types of cells—neurons and neuroglia. Neuroglia are smaller cells but they greatly outnumber neurons, perhaps by as much as 25 times. Neuroglia support, nourish, and protect neurons, and maintain the interstitial fluid that bathes them. Unlike neurons, neuroglia continue to divide throughout an individual’s lifetime. [Neurons does not undergo mitosis process because they lack centrioles.] Both neurons and neuroglia differ structurally depending on whether they are located in the central nervous system or the peripheral nervous system. These differences in structure correlate with the differences in function of the central nervous system and the peripheral nervous system. Neurons Neurons (nerve cells) possess electrical excitability, the ability to respond to a stimulus and convert it into an action potential. A stimulus is any change in the environment that is strong enough to initiate an action potential. Example: Outside of the body (touch, pain sensation) and Inside of the body (hormonal imbalance) An action potential (nerve impulse) is an electrical signal that propagates (travels) along the surface of the membrane of a neuron. It begins and travels due to the movement of ions (such as sodium and potassium) between interstitial fluid and the inside of a neuron through specific ion channels in its plasma membrane. Once begun, a nerve impulse travels rapidly and at a constant strength. Nerve impulses travel these great distances at speeds ranging from 0.5 to 130 meters per second. Parts of a Neuron Most neurons have three parts: (1) a cell body, (2) dendrites, and (3) an axon Classification of Neurons structural and functional features are used to classify the various neurons in the body. Structural Classification 1. Multipolar neurons usually have several dendrites and one axon Most neurons in the brain and spinal cord are of this type, as well as all motor neurons 2. Bipolar neurons have one main dendrite and one axon. They are found in the retina of the eye, the inner ear, and the olfactory area of the brain. 3. Unipolar neurons have dendrites and one axon that are fused together to form a continuous process that emerges from the cell body Neuroglia Neuroglia or glia make up about half the volume of the CNS. Their name derives from the idea of early histologists that they were the “glue” that held nervous tissue together. We now know that neuroglia are not merely passive bystanders but rather actively participate in the activities of nervous tissue. Generally, neuroglia are smaller than neurons, and they are 5 to 25 times more numerous. In contrast to neurons, glia do not generate or propagate action potentials, and they can multiply and divide in the mature nervous system. Of the six types of neuroglia, four—astrocytes, oligodendrocytes, microglia, and ependymal cells—are found only in the CNS. The remaining two types—Schwann cells and satellite cells—are present in the PNS.

PROFESSIONAL Integrity, Honesty and Responsibility ppt (1).pdfBhumikaSingh805349

Professional integrity, honesty, and responsibility are fundamental pillars of ethical conduct in the workplace. Integrity involves consistently upholding ethical standards and maintaining a strong moral compass, ensuring that actions align with core values and principles. Honesty emphasizes transparency and truthfulness in communication and actions, fostering trust among colleagues, clients, and stakeholders. Responsibility focuses on taking ownership of one’s actions and their consequences, fulfilling commitments, and being accountable for decisions made in a professional context. Together, these qualities promote a positive work environment, enhance relationships, and contribute to long-term success and respect in any profession.

Pharmacy Act, 1948 – Regulation of Pharmacy Education and Profession in IndiaDr.Navaneethakrishnan S

This presentation provides a detailed overview of the Pharmacy Act, 1948, which governs the education, registration, and regulation of pharmacists in India. It covers the history, objectives, and key provisions of the Act, including the establishment of the Pharmacy Council of India (PCI) and State Pharmacy Councils (SPC). The roles and responsibilities of these councils, including the design of educational regulations, approval of pharmacy institutions, maintenance of central and state registers of pharmacists, and regulatory enforcement, are discussed in detail. The presentation also highlights foreign qualification recognition, inspection protocols, and penalties for non-compliance. Essential for pharmacy students, educators, regulatory professionals, and industry stakeholders.

Plasma and Red Blood Cells - Copy - Copy_AntiCopy.pdfMedicoseAcademics

Delve deep into the intricate world of blood physiology with “Plasma and Red Blood Cells,” a comprehensive lecture presented by Dr. Faiza, Assistant Professor of Physiology. This presentation is meticulously designed for students, educators, and healthcare professionals to enhance their understanding of hematology and the critical roles played by various blood components. In this lecture, you will: Examine Blood Composition: Learn how blood constitutes approximately 8% of total body weight, with precise volumes differing between genders. The presentation breaks down blood into its two fundamental components—plasma and blood cells—and explains their distribution and essential functions in the body. Understand Plasma Functions and Composition: Discover the key role of plasma as a transport medium for nutrients, waste products, hormones, and ions. The lecture details the high water content (~90%), the balance of inorganic (e.g., Na⁺, Cl⁻, HCO₃⁻, K⁺, Ca²⁺) and organic substances (notably plasma proteins), and how these components contribute to maintaining homeostasis, temperature regulation, and pH balance. Classify Plasma Proteins: Explore the classification of plasma proteins into albumins, globulins (alpha, beta, and gamma), and fibrinogen. Learn about their individual functions, such as maintaining colloid osmotic pressure, facilitating transport of poorly soluble substances, and contributing to immune defense and clotting processes. Analyze Hematocrit and Packed Cell Volume (PCV): Understand the significance of hematocrit or PCV as a measure of the proportion of erythrocytes in blood, including the average values observed in men and women. This metric is crucial for assessing blood viscosity and overall health. Study the Structure and Function of Erythrocytes: Gain insight into the unique characteristics of red blood cells, including their biconcave disc shape, deformability, and the absence of organelles, which all play a role in optimizing oxygen transport. Detailed discussions cover the enzymes involved in RBC metabolism and the physiological basis for their limited lifespan. Relate to Clinical and Physiological Contexts: The lecture also connects these fundamental concepts to clinical scenarios, explaining how alterations in blood composition can impact oxygen delivery, acid-base balance, and overall metabolic function. It provides a solid foundation for understanding common hematological disorders and the body’s adaptive mechanisms in various pathological conditions. Each slide is carefully structured to build a comprehensive picture of blood components and their interplay, supported by visual aids such as flow diagrams, comparative charts, and schematic representations. Dr. Faiza’s expertise is evident as she translates complex physiological processes into accessible and practical knowledge, making this presentation a valuable resource for enhancing your medical education.

What is PharmD.pptx Its about pharm.d coursesurisettirajesh7

World Health Day 2025 - Importance of Mental HealthJeenasikho Lifecare LTD

Good Automated Laboratory Practices (GALP) Standards, Compliance, and Impleme...Dr. Smita Kumbhar

Good Automated Laboratory Practices (GALP) refers to a structured framework designed to ensure the reliability, accuracy, and integrity of data generated by automated laboratory systems. These practices encompass standard operating procedures (SOPs), regulatory compliance, software validation, and personnel training to maintain consistency in laboratory operations. GALP is essential for laboratories that rely on automation to process high volumes of data while ensuring regulatory adherence, particularly in pharmaceutical, biotechnology, and clinical research environments. Principles of GALP The fundamental principles of GALP include: 1. Data Integrity: Ensuring accurate, reliable, and tamper-proof data recording and analysis. 2. Regulatory Compliance: Adhering to national and international standards such as ISO, 21 CFR Part 11, and QCI guidelines. 3. Standardized Processes: Implementing well-defined SOPs to guide laboratory operations. 4. System Validation: Regularly verifying automated instruments and software for functionality and compliance. 5. Personnel Training: Ensuring that laboratory staff are adequately trained to operate automated systems efficiently and accurately. 6. Risk Management: Identifying and mitigating potential risks in automated workflows. 7. Continuous Improvement: Periodic reviews and updates to laboratory practices to incorporate technological advancements. GALP Requirements To implement GALP, laboratories must adhere to certain requirements: 1. Standardized Documentation: Maintaining comprehensive records of laboratory procedures and automation processes. 2. Software and Instrument Validation: Ensuring that all automated systems function as intended and comply with regulatory requirements. 3. Data Security Measures: Implementing encryption, access control, and audit trails for secure data management. 4. Regulatory Compliance: Aligning with relevant regulations such as 21 CFR Part 11, ISO standards, and QCI guidelines. 5. Personnel Competency: Conducting periodic training and assessments for laboratory staff. 6. Audit Readiness: Preparing for internal and external inspections by maintaining up-to-date documentation. SOPs of GALP Standard Operating Procedures (SOPs) form the backbone of GALP. These SOPs cover: 1. Instrument Calibration: Regular calibration and validation of automated instruments. 2. Data Entry and Management: Guidelines on recording, storing, and retrieving data in compliance with regulatory standards. 3. Sample Handling: Ensuring standardized procedures for sample collection, processing, and storage. 4. Software Usage and Maintenance: Guidelines on software validation, updates, and troubleshooting. 5. Audit Trail Management: Recording and reviewing all modifications made to electronic data. 6. Corrective and Preventive Actions (CAPA): Addressing non-compliance and implementing necessary improvements. Training Documentation A key aspect of GALP is personnel training, which includes: 1. Training Plans

Let's Talk About It: Ovarian Cancer (Making Meaning after a Cancer Diagnosis)RheannaRandazzo

Making meaning from hardship is a complex conversation. Many cancer survivors feel the delicate balance between making meaning and the internalized or external pressure that often follows a cancer diagnosis. Questions such as “What now?” are common when treatment ends. Well-meaning friends and family may subtly (or not so subtly) expect us to behave or view the world differently. If figuring out who you are now feels puzzling, join us on Wednesday, December 11th. Together, we will discuss how changes in your identity and perspective are a valid and essential part of this journey. Research has shown us how making meaning after hardship facilitates adjustment and well-being.

URINARYBLADDER gross features with relations.pptxsudha991503

Erythropoiesis, stages and its regulationMedicoseAcademics

This presentation, "Erythropoiesis," by Dr. Faiza, Assistant Professor of Physiology, offers an in-depth exploration of the formation and regulation of red blood cells (RBCs). Designed for medical and health professional students, as well as educators, the lecture systematically covers: Learning Objectives: Describing the structure of erythrocytes in relation to their functions. Explaining the process of erythropoiesis through clear, schematic representations. Analyzing the regulation of red blood cell production, with a focus on the role of erythropoietin. Key Topics Covered: Production of Red Blood Cells: An overview of erythropoiesis from embryonic development (yolk sac, liver, spleen) to adult bone marrow as the exclusive site of RBC production. Bone Marrow Dynamics: Differentiating between red and yellow marrow, and understanding the changes in hematopoiesis across the lifespan. Hematopoiesis: Detailed explanation of multipotential hematopoietic stem cells (HSCs), colony-forming units (CFUs), and the commitment to specific blood cell lineages. Regulation of Blood Cell Formation: Insight into the role of growth and differentiation inducers, external factors like hypoxia, and the primary regulatory function of erythropoietin (EPO). Clinical Implications: Discussion on conditions that stimulate RBC production, the concept of synthetic erythropoietin in managing anemia (especially in chronic kidney failure and chemotherapy patients), and key points to consider for further research. Presentation Structure: The slides guide the viewer from foundational concepts of blood composition and cell formation to more complex regulatory mechanisms, ensuring a thorough understanding of both the physiological processes and their clinical relevance. This lecture not only enhances your understanding of erythropoiesis but also serves as a vital resource for those interested in the broader aspects of hematology and medical education. Whether you're a student looking to consolidate your knowledge or an educator seeking effective teaching materials, this presentation provides clear visuals, structured content, and practical insights into the dynamic process of red blood cell formation.

Detailed Overview of the Drugs and Cosmetics Act, 1940 & RulesDr.Navaneethakrishnan S

This presentation provides a comprehensive overview of the Drugs and Cosmetics Act, 1940, and its associated rules from 1945. It covers the objectives of the Act, its significance in regulating the import, manufacture, distribution, and sale of drugs and cosmetics in India. Key definitions such as drugs, cosmetics, misbranded, adulterated, and spurious products are explained in detail. Additionally, it highlights the legal definitions and important schedules to the Act, ensuring clarity on regulatory standards. Essential roles such as Drug Inspector and Government Analyst are also discussed. This presentation is useful for pharmacy students, regulatory professionals, and individuals interested in pharmaceutical law.

A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing ...PVI, PeerView Institute for Medical Education

Chair, Kathleen N. Moore, MD, MS, David M. O'Malley, MD, and Bhavana Pothuri, MD, MS, discuss ovarian cancer in this CME/MOC/NCPD/AAPA/IPCE activity titled “A New Era in Treating Advanced Ovarian Cancer: Practical Tips for Maximizing the Use of PARP Inhibitors, Immunotherapy, and ADCs.” For the full presentation, downloadable Practice Aids, and complete CME/MOC/NCPD/AAPA/IPCE information, and to apply for credit, please visit us at https://bit.ly/48VGDQV. CME/MOC/NCPD/AAPA/IPCE credit will be available until April 14, 2026.

Ethics in Clinical Research Regulation including historical perspective for (...Om Mahajan

SYNAPSE AND NEUROTRANSMITTERS (Nervous System).pptxPranaliChandurkar2

There is always more than one neurone involved in the transmission of a nerve impulse from its origin to its destination, whether it is sensory or motor. There is no physical contact between two neurones. Synapse: The point at which the nerve impulse passes from the presynaptic neurone to the postsynaptic neurone. Presynaptic Neurons: The neurons that carries action potential to the synapse. Postsynaptic Neurons: Neurons that carries action potential away from the synapse. Synaptic knobs or terminal boutons: At its free end, the axon of the presynaptic neurone breaks up into minute branches that terminate in small swellings. These are in close proximity to the dendrites and the cell body of the postsynaptic neurone. The space between them is the synaptic cleft. Synaptic knobs contain spherical membrane bound synaptic vesicles, which store a chemical (the neurotransmitter) that is released into the synaptic cleft. Neurotransmitters are synthesised by nerve cell bodies, actively transported along the axons and stored in the synaptic vesicles. They are released by exocytosis in response to the action potential in the presynaptic neurons and diffuse across the synaptic cleft. They act on specific receptor sites on the postsynaptic membrane. Their action is short lived, because immediately they have acted on the postsynaptic cell such as a muscle fibre, they are either inactivated by enzymes or taken back into the synaptic knob. Some important drugs act by mimicking, neutralising (antagonising), or prolonging normal actions of neurotransmitters. Neurotransmitters usually have an excitatory effect on postsynaptic receptors but they are sometimes inhibitory. There are more than 50 neurotransmitters in the brain and spinal cord including noradrenaline (norepinephrine), adrenaline (epinephrine), dopamine, histamine, serotonin, gamma aminobutyric acid (GABA) and acetylcholine. Other substances, such as Neuropeptides (enkephalins, endorphins and substance P) have specialised roles in, for example, transmission of pain signals. Excitatory neurotransmitters: Acetylcholine, Norepinephrine, Dopamine (Initiate New Impulse) Inhibitory neurotransmitters: GABA, Serotonin, Glycine (Reduces the chance of new impulse, Hyperpolarization).

Drug_Design PRESENTSTION B.pharm 6th sem. IGNTU AMARKANTAK M.P.IGNTU AMARKANTAK (M.P.)

JOINT DISLOCATION.pptx FOR NURSING STUDENTSKIRAN KARETHA

DEFINITION: joint dislocation is a condition when bone moves out from its original place or bone slips out of a joint. Common joints for dislocation are shoulder, knee, hip, ankle and elbow. Causes: May occur in any situation, whether it being the sporting arena or routine daily chores. Trauma, falls or motor vehicle accidents Underlying pathological condition such as TB, inflammatory disorders. Previous joint dislocation result in weakening of tendons, ligament and muscle which may be a cause of recurrent dislocations. Clinical manifestation: Pain Tenderness Warmth and redness Loss of motion Tingling sensation Swelling Discolored skin Diagnostic evaluation: X-ray: radiograph of the affected part should include anterior, posterior and lateral views. It is used to produce image of internal tissues, bones and organs onto film. CT Scan Magnetic resonance imaging: a diagnostic procedure that uses a combination of large magnets, radiofrequencies and a computer to produce more detailed and precise image of structures within body than x-ray. Management: Initial first aid management STOP S: (stop) immediately immobilize the patient`s dislocated joint as there may be strong positivity of fracture. T: (Talk) ask the questions if the patient is conscious. O: (Observe) observe closely for any injury, swelling, deformity or bleeding. P: (Prevent) prevent further injury to the patients by conducting a whole body assessment. RICE -R: (Rest) sit or lie the patient down in comfortable position. -I: (Ice) use cold packs to cool compress the affected area. -C: (Compression) wrap the compression bandage around the limb to support it and restrict movement. -E: (Elevate) the injured limb should be supported above the level of heart. Refer the patient to the hospital if required. Ascertain if the patient is conscious by verbal and physical need. If the patient is unconscious then follow: C: (Compression) initiate CPR. A: (Airway) ensure airway is clear by jaw thrust, chin lift head tilt maneuver. B: (Breathing) listen and feel the signs of life. D: (Defibrillator) perform defibrillator if CPR fails. REDUCTION: Types of reduction: 1- Closed reduction – in closed reduction a doctor physically moves the bone back into place without surgically exposing the bone. 2- Open reduction- in open reduction orthopedic surgeons reposition the dislocated bone surgically so that bone is back in their proper alignment.

Cardiac Amplifiers: A Deep Dive into InotropesViresh Mahajani

Inotropic drugs are vital in managing acute heart failure and cardiogenic shock, directly influencing myocardial contractility. This presentation delves into their mechanisms, clinical applications, and nursing considerations. We'll explore how positive inotropes, like dobutamine and milrinone, enhance calcium influx, boosting cardiac output but also increasing myocardial oxygen demand. Conversely, we'll discuss the nuances of negative inotropes, such as beta-blockers, used in specific scenarios to reduce workload. A critical focus will be on the pharmacokinetics and pharmacodynamics of these agents, highlighting their impact on hemodynamic parameters. We'll examine the importance of meticulous monitoring, including blood pressure, heart rate, and ECG, to optimize therapy and mitigate adverse effects like arrhythmias and hypotension. Nursing implications will emphasize safe administration, patient education, and recognizing signs of drug toxicity. Case studies will illustrate the practical application of inotropic therapy in various clinical settings, reinforcing the importance of this knowledge in critical care.

Autocoids mcq.ankush goyal gmc patiala punjabDr Ankush goyal

Lipid Autocoids: A Comprehensive Overview Introduction Lipid autocoids, also known as eicosanoids and related lipid mediators, are bioactive molecules derived from polyunsaturated fatty acids (PUFAs). These molecules play crucial roles in inflammation, immunity, hemostasis, cardiovascular function, and various physiological and pathological processes. Unlike classical hormones, lipid autocoids act locally, exerting their effects at or near their site of synthesis. This document provides an in-depth analysis of lipid autocoids, covering their biosynthesis, classification, physiological roles, and clinical significance. Classification of Lipid Autocoids Lipid autocoids are broadly classified into the following categories: 1. Eicosanoids (Derived from Arachidonic Acid) Prostaglandins (PGs) Thromboxanes (TXs) Leukotrienes (LTs) Lipoxins (LXs) 2. Specialized Pro-resolving Mediators (SPMs) Resolvins Protectins Maresins 3. Endocannabinoids Anandamide (AEA) 2-Arachidonoylglycerol (2-AG) 4. Platelet-Activating Factor (PAF) 5. Sphingolipid-Derived Mediators Sphingosine-1-Phosphate (S1P) Ceramides Biosynthesis of Lipid Autocoids Lipid autocoids are derived from membrane phospholipids through enzymatic pathways: 1. Phospholipase A2 (PLA2) Activation: PLA2 catalyzes the release of arachidonic acid (AA) from membrane phospholipids. 2. Cyclooxygenase (COX) Pathway: Converts AA into prostaglandins and thromboxanes. COX-1: Constitutive enzyme (housekeeping functions). COX-2: Inducible enzyme (inflammation and pain response). 3. Lipoxygenase (LOX) Pathway: Converts AA into leukotrienes and lipoxins. 5-LOX: Leads to leukotrienes (inflammation, bronchoconstriction). 12-LOX & 15-LOX: Lead to lipoxins (anti-inflammatory action). 4. Cytochrome P450 (CYP) Pathway: Converts AA into epoxyeicosatrienoic acids (EETs), which regulate vascular tone. 5. Endocannabinoid Biosynthesis: Derived from membrane phospholipids via enzymatic reactions. Degraded by fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). Physiological Roles of Lipid Autocoids 1. Inflammation and Immune Response Prostaglandins (e.g., PGE2) modulate fever and pain. Leukotrienes mediate allergic responses and asthma. Lipoxins and resolvins promote resolution of inflammation. 2. Cardiovascular System Thromboxanes (TXA2) induce platelet aggregation and vasoconstriction. Prostacyclin (PGI2) inhibits platelet aggregation and promotes vasodilation. EETs regulate blood pressure and vascular homeostasis. 3. Pulmonary Function Leukotrienes (LTC4, LTD4, LTE4) are potent bronchoconstrictors. PGE2 has bronchodilatory effects. 4. Renal Function Prostaglandins regulate glomerular filtration rate and sodium excretion. EETs contribute to natriuresis. 5. Neurotransmission and Pain Endocannabinoids modulate pain perception and neuroprotection. Prostaglandins contribute to central pain sensitization. 6. Reproductive System P

AI Trends in Creative Operations 2024 by Artwork Flow.pdfmarketingartwork

Creative operations teams expect increased AI use in 2024. Currently, over half of tasks are not AI-enabled, but this is expected to decrease in the coming year. ChatGPT is the most popular AI tool currently. Business leaders are more actively exploring AI benefits than individual contributors. Most respondents do not believe AI will impact workforce size in 2024. However, some inhibitions still exist around AI accuracy and lack of understanding. Creatives primarily want to use AI to save time on mundane tasks and boost productivity.

Skeleton Culture CodeSkeleton Technologies

Organizational culture includes values, norms, systems, symbols, language, assumptions, beliefs, and habits that influence employee behaviors and how people interpret those behaviors. It is important because culture can help or hinder a company's success. Some key aspects of Netflix's culture that help it achieve results include hiring smartly so every position has stars, focusing on attitude over just aptitude, and having a strict policy against peacocks, whiners, and jerks.

More Related Content

Recently uploaded (20)